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1-Boc-piperazine, 99%, Thermo Scientific Chemicals Product Code.: 11378076
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1-Boc-piperazine, 99%, Thermo Scientific Chemicals

Product Code. 11378076
1 g
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1 g
5 g
25 g
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Product Code. 11378076

Brand: Thermo Scientific Alfa Aesar L13363.03

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Description

1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

Solubility
Soluble in ethyl acetate, methanol and water.

Notes
Hygroscopic. Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 57260-71-6
Molecular Formula C9H19N2O2
Molecular Weight (g/mol) 187.26
MDL Number MFCD00075265
InChI Key CWXPZXBSDSIRCS-UHFFFAOYSA-O
Synonym 1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl esterShow MoreShow Less
PubChem CID 143452
IUPAC Name tert-butyl piperazine-1-carboxylate
SMILES CC(C)(C)OC(=O)N1CC[NH2+]CC1

Specifications

Melting Point 44°C to 48°C
Quantity 1 g
Beilstein 879985
Sensitivity Air Sensitive
Solubility Information Soluble in ethyl acetate,methanol and water.
Formula Weight 186.26
Percent Purity 99%
Chemical Name or Material 1-Boc-piperazine

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberX11C002 Certificate TypeCertificate of Analysis Date25/11/2024 Catalog NumberL13363.06,L13363.03,L13363.14
Lot Number10242524 Certificate TypeCertificate of Analysis Date04/08/2022 Catalog NumberL13363.06,L13363.03,L13363.14
Lot NumberX11C002 Certificate TypeCertificate of Analysis Date08/12/2021 Catalog NumberL13363.06,L13363.03,L13363.14
Lot Number10202451 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberL13363.06,L13363.03,L13363.14
Lot Number61001114 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog NumberL13363.06,L13363.03,L13363.14

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