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CDC27 Mouse, Unlabeled, Clone: 35, BD

Mouse Monoclonal Antibody

343.00 € - 675.00 €

Specifications

Antigen CDC27
Clone 35
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15865469
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BD Biosciences
610454
50 μg
343.00 €
1 set
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15875469
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BD Biosciences
610455
150 μg
675.00 €
1 set
Please to purchase this item. Need a web account? Register with us today!
Description

Description

CDC16 and CDC27 were discovered in yeast as genes essential for the G2/M transition of the cell cycle. The human homologues of CDC16 and CDC27were cloned and found to encode proteins of 72kDa and 97kDa, respectively. Biochemical and subcellular localization experiments have shown that CDC16 and CDC27 are novel components of the mitotic spindle centrosome in human cells. In HeLa cells, there are about 100,000 copies of each protein per cell. Although its precise role during mitosis remains to be determined, CDC16 appears to be required for cyclin degradation in yeast. Wild type CDC27 is required for the initiation of anaphase. Immunofluorescence studies have shown that both proteins are components of the centrosome in the absence of spindle fibers.

Specifications

Specifications

CDC27
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG2b
Affinity Purified
35
Western Blot
Unconjugated
RUO
Canine, Human, Mouse, Rat
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Store undiluted at -20°C.
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Product Certifications

For Research Use Only.