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ATR Monoclonal Antibody (3G6D2), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA548382
This item is not returnable.
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Description
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Specifications
| ATR | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| Q13535 | |
| ATR | |
| Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. Coli. | |
| 100 μg | |
| Primary | |
| Human | |
| Liquid |
| ELISA, Flow Cytometry, Immunohistochemistry, Western Blot | |
| 3G6D2 | |
| Unconjugated | |
| ATR | |
| 2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8 | |
| Mouse | |
| Protein G | |
| RUO | |
| 545 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| IgG1 |