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Thermo Scientific Chemicals Caspase-3 Inhibitor III
Chemical Identifiers
| CAS | 285570-60-7 |
|---|---|
| Molecular Formula | C21H31ClN4O11 |
| Synonym | Ac-DEVD-CMK; N-Acetyl-Asp-Glu-Val-Asp chloromethyl ketone |
Description
A potent, cell-permeable, and irreversible inhibitor of caspase-3; also inhibits caspases -6, -7, -8, and -10. Commonly used at concentrations up to 100 -M to examine the role of caspase-3-dependent apoptosis
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Chemical Identifiers
| 285570-60-7 | |
| C21H31ClN4O11 | |
| Ac-DEVD-CMK; N-Acetyl-Asp-Glu-Val-Asp chloromethyl ketone |
Specifications
| Off-white to brown | |
| A potent, cell-permeable, and irreversible inhibitor of caspase-3; also inhibits caspases -6, -7, -8, and -10. Commonly used at concentrations up to 100 →M to examine the role of caspase-3-dependent apoptosis | |
| C21H31ClN4O11 | |
| Ac-DEVD-CMK; N-Acetyl-Asp-Glu-Val-Asp chloromethyl ketone | |
| Powder | |
| CC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(C)=O)C(=O)NC(CC(O)=O)C(=O)CCl | |
| 550.95 |
| -30°C to -10°C | |
| 285570-60-7 | |
| 550.94 | |
| Soluble in DMSO | |
| ATNOUPFYBMVFLD-UHFFFAOYNA-N | |
| 3-{2-[4-carboxy-2-(3-carboxy-2-acetamidopropanamido)butanamido]-3-methylbutanamido}-5-chloro-4-oxopentanoic acid |
Safety and Handling
Recommended Storage : Store at -20°C
RUO – Research Use Only