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CD11b, FITC, clone: VIM12, Invitrogen™

Mouse Monoclonal Antibody

298.00 € - 988.00 €

Specifications

Antigen CD11b
Clone VIM12
Applications Flow Cytometry
Classification Monoclonal
Conjugate FITC
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
10785703
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Invitrogen
CD11B01
0.5 mL
298.00 €
Each
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10180273
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Invitrogen
CD11B014
2 mL
988.00 €
Each
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Description

Description

CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X, and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, and blood monocytes. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue.

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.
Specifications

Specifications

CD11b
Flow Cytometry
FITC
Mouse
Human
P11215
3684
Human CD11b (Mac-1)
Primary
Store at 2 - 8 °C.
ITGAM
VIM12
Monoclonal
Liquid
ASR, ASR/IVD
PBS with BSA and 0.1% sodium azide
CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6, Integrin alpha M
ITGAM
IgG1
Purified
Antibody
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SDS
Documents

Documents

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