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Deguelin, MedChemExpress
MedChemExpress Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
71.55 € - 464.40 €
Specifications
| Chemical Name or Material | Deguelin |
|---|---|
| CAS | 522-17-8 |
| Color | Light Yellow |
| Purity Grade Notes | Research |
| Molecular Formula | C23H22O6 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16485678
|
Medchem Express
HY-13425 |
10 mg |
132.30 €
10mg |
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|
16451847
|
Medchem Express
HY-13425 |
50 mg |
464.40 €
50mg |
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|
16418377
|
Medchem Express
HY-13425 |
5 mg |
71.55 €
5mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.Specifications
| Deguelin | |
| Light Yellow | |
| C23H22O6 | |
| DMSO : 100 mg/mL (253.54 mM; Need ultrasonic) | |
| 394.42 | |
| 98.0% | |
| Solid |
| 522-17-8 | |
| Research | |
| (-)-Deguelin (-)-cis-Deguelin | |
| O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14 | |
| 394.42 | |
| Research | |
| Cancer-Kinase/protease |
Safety and Handling
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only