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  7. Deoxycholic acid, 99%, Thermo Scientific Chemicals

Deoxycholic acid, 99%, Thermo Scientific Chemicals

Product Code. 11410551
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Quantity:
25 g
100 g
500 g

Description

Deoxycholic acid has been used in a modified procedure to recover 40-80% of a protein from a 1 μg/mL solution. It forms complexes with fatty acid. Used as an emulsifying agent in food, a precursor in the synthesis of cortisone, and a gallbladder stimulant. It has been used to study assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Deoxycholic acid has been used in a modified procedure to recover 40-80% of a protein from a 1 µg/mL solution. It forms complexes with fatty acid. Used as an emulsifying agent in food, a precursor in the synthesis of cortisone, and a gallbladder stimulant. It has been used to study assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.

Solubility
The free acid is soluble at 0.044 g/L in water at 20°C. Solubility in methanol is almost transparent.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 83-44-3
Molecular Formula C24H40O4
Molecular Weight (g/mol) 392.58
MDL Number MFCD00003673
InChI Key KXGVEGMKQFWNSR-LLQZFEROSA-N
Synonym deoxycholic acid, deoxycholate, desoxycholic acid, choleic acid, cholerebic, cholorebic, degalol, deoxycholatic acid, droxolan, pyrochol
PubChem CID 222528
ChEBI CHEBI:28834
IUPAC Name (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
SMILES [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

Specifications

Melting Point 172°C to 176°C
Quantity 100 g
Beilstein 3219882
Merck Index 14,2899
Solubility Information The free acid is soluble at 0.044g/L in water at 20°C. Solubility in methanol is almost transparent.
Optical Rotation +54° (c=2 in Ethanol)
Formula Weight 392.58
Percent Purity 99%
Chemical Name or Material Deoxycholic acid

Safety and Handling

compliance-icons
Product Identifier
  • Deoxycholic acid
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • LONG-TERM AQUATIC HAZARD Chronic 3
 Hazard Statement
  • H302-Harmful if swallowed.
  • H412-Harmful to aquatic life with long lasting effects.
 Precautionary Statement
  • P264-Wash face, hands and anyexposed skin thoroughly after handling.
  • P273-Avoid release to the environment.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : Deoxycholic acid

RUO – Research Use Only

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