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Dihydrokainic acid, Tocris Bioscience™

Product Code. 18054342
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50 mg
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Description

EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake

Dihydrokainic acid is an EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake (Ki = 23 μM). 130-fold selective over EAAT1 and EAAT3 (Ki > 3 mM).

Chemical Identifiers

CAS 52497-36-6
Molecular Formula C10H17NO4
Molecular Weight (g/mol) 215.25
MDL Number MFCD03412037
InChI Key JQPDCKOQOOQUSC-OOZYFLPDSA-N
Synonym dihydrokainic acid, dihydrokainate, dihydrokainic acid, natural, 2s,3s,4r-2-carboxy-4-isopropyl-3-pyrrolidineacetic acid, 3s,4r-3-carboxymethyl-4-propan-2-yl-l-proline, 2s,3s,4r-2-carboxy-4-1-methylethyl-3-pyrrolidineacetic acid, 2s,3s,4r-3-carboxymethyl-4-propan-2-yl pyrrolidine-2-carboxylic acid, 2s,3s,4r-3-carboxymethyl-4-isopropylpyrrolidine-2-carboxylic acid, 1ftk, 1xhy
PubChem CID 107883
ChEBI CHEBI:43562
IUPAC Name (2S,3S,4R)-3-(carboxymethyl)-4-(propan-2-yl)pyrrolidine-2-carboxylic acid
SMILES CC(C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O

Specifications

Quantity 1 mg
Formula Weight 215.25
Percent Purity >98%
Chemical Name or Material Dihydrokainic acid
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