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Doxorubicin Hydrochloride, Fisher BioReagents

Product Code. 11413074
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Quantity:
1 mg
5 mg
10 mg
50 mg
Packaging:
Amber Glass
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Doxorubicin Hydrochloride

Doxorubicin HCL is a chemotherapeutic agent. Antitumor, immunosuppressive, and antibiotic agent. It blocks RNA polymerase and reverse transcriptase. Also inhibits nucleic acid synthesis.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 25316-40-9
Molecular Formula C27H30ClNO11
Molecular Weight (g/mol) 579.98
MDL Number MFCD00077757,MFCD00077757,MFCD00941448
InChI Key MWWSFMDVAYGXBV-FGBJBKNOSA-N
Synonym doxorubicin hydrochloride, adriamycin, doxorubicin hcl, adriacin, adriblastina, rubex, adriamycin hydrochloride, adriblastin, adriamycin pfs
PubChem CID 129626538
IUPAC Name (7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
SMILES [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O

Specifications

Decomposition Information 216°C
Melting Point 216°C
Color Orange
Assay Percent Range (by HPLC): ≥95%
Packaging Amber Glass
Quantity 5 mg
Merck Index 15, 3487
Solubility Information Soluble in water
Formula Weight 580
Physical Form Powder or Solid
Chemical Name or Material Doxorubicin Hydrochloride
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Safety and Handling

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Product Identifier
  • Doxorubicin hydrochloride
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 4
  • Carcinogenicity Category 1B
  • Serious eye damage/eye irritation Category 1
  • Germ cell mutagenicity Category 1B
  • Reproductive toxicity Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H318-Causes serious eye damage.
  • H340-May cause genetic defects.
  • H350-May cause cancer.
  • H315-Causes skin irritation.
  • H361fd-Suspected of damaging fertility. Suspected of damaging the unborn child.
  • H335-May cause respiratory irritation.
  • H302-Harmful if swallowed.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
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