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Human FRAP1 (mTOR), GST Tag Recombinant Protein
Human FRAP1 (mTOR), GST Tag Recombinant Protein
Brand: Invitrogen PR8683B
This item is not returnable.
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Description
FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.
Specifications
| NP_004949.1 | |
| Protein Assays and Analysis, Kinase Assay | |
| 163.9kDa | |
| 100μg | |
| For research use only. Not for use in diagnostic procedures | |
| FRAP1 (mTOR) | |
| FRAP1 (mTOR) was pre-diluted in enzyme dilution buffer and assayed in 50mM HEPES (pH 7.5), 10mM MnCl2, 1mM EGTA, 2.5mM DTT, 0.01% Polysorbate 20, 100μM ATP, 500μg/mL PHAS-1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| FRAP1 (mTOR) Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| 80% by SDS-PAGE |
| 0.45mg/mL | |
| Frozen | |
| FRAP1 (mTOR) Recombinant Human Protein | |
| –80°C | |
| 1 Each | |
| FRAP1 (mTOR) Recombinant Human Protein | |
| PIKK kinase family | |
| 34nmoles of phosphate transferred to PHAS-1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 5μg/mL | |
| GST Tag | |
| Frozen |
For Research Use Only. Not for use in diagnostic procedures.