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Tocris Bioscience™ Galiellalactone

STAT3 inhibitor; active in vivo

Brand: Tocris Bioscience™ 6218/500U

245.35 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.

Product Code. 18751368

310.00 € / 500µg

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Description

Galiellalactone is a STAT3 inhibitor. Irreversibly binds STAT3 and inhibits binding to DNA. Inhibits IL-6-dependent JAK/STAT signaling. Induces cell-cycle arrest in G2/M phase and apoptosis in androgen-insensitive prostate cancer cells via activation of ATM/ATR pathway. Also destabilizes microtubules and inhibits cell migration. Exhibits anticancer effects in a mouse tumor xenograft model.

Specifications

Product Type	Inhibitor
CAS	133613-71-5
Formula Weight	194.23g/mol
For Use With (Application)	STAT Inhibitors

Target Proteins	STAT
Molecular Formula	C₁₁H₁₄O₃
Content And Storage	Store at -20°C
Quantity	500 μg

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Tocris Bioscience™ Galiellalactone

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