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Thermo Scientific™ GeneBLAzer™ CALCRL:RAMP3-CRE-bla FreeStyle™ 293F Cells
The GeneBLAzer™ CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells contain the human Amylin Receptor 2 (CALCRL:RAMP3), stably integrated into the CellSensor™ CRE-bla Freestyle™ 293F cell line.
Brand: Thermo Scientific™ K1439
This item is not returnable.
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Description
The GeneBLAzer™ CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells contain the human Amylin Receptor 2 (CALCRL:RAMP3), (Accession # NM_005795.3 NM_005856.1) stably integrated into the CellSensor™ CRE-bla Freestyle™ 293F cell line. CellSensor™ CRE-bla Freestyle™ 293F cells (Cat. No. K1130) contain a beta-lactamase (bla) reporter gene under control of the cAMP response element (CRE).
CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells are functionally validated for Z'-factor and EC50 concentrations of Adrenomedullin(1-52). In addition, CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
Specifications
| NM_005855.2 | |
| Dividing Cells | |
| GeneBLAzer™ CALCRL:RAMP3-CRE-bla FreeStyle™ 293F Cells, 8 x 106 Cells, ∽8,000,000 cells/vial at 8,000,000 cells/mL Quantity of Cells, FreeStyle™ 293-F Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage | |
| Pharma and biopharma, drug discovery and development, target and lead identification and validation, G-protein coupled receptor biology, cell-based GPCR reporter assays | |
| GeneBLAzer™ CALCRL:RAMP3-CRE-bla FreeStyle™ 293F Cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: GeneBLAzer™ CALCRL:RAMP3-CRE-bla Freestyle™ 293F cells, GeneBLAzer™ CALCRL:RAMP3-CRE-bla Freestyle™ 293F Assay Protocol, Certificate of Analysis | |
| Freestyle™, GeneBLAzer™ | |
| BLA (Beta-Lactamase) | |
| CALCRL:RAMP3 | |
| FreeStyle 293-F Cells | |
| GPCR |
| Cell-based beta lactamase reporter gene | |
| LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • GeneBLAzer™ CALCRL:RAMP3-CRE-bla Freestyle™ 293F cells • GeneBLAzer™ CALCRL:RAMP3-CRE-bla Freestyle™ 293F Assay Protocol • Certificate of Analysis The GeneBLAzer™ CALCRL:RAMP3-CRE-bla Freestyle™ 293F cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
|
| Fluorescence | |
| CALCRL:RAMP3 | |
| Single Cell Clone Origin | |
| 8 x 106 Cells | |
| FreeStyle™ 293-F | |
| Cell Line | |
| GeneBLAzer™ |
For Research Use Only. Not for use in diagnostic procedures.