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Thermo Scientific™ GeneBLAzer™ GRPR CHO-K1 DA Assay Kit

The GeneBLAzer™ GRPR-NFAT-bla CHO-K1 cells contain the human Gastrin Releasing Peptide Receptor (GRPR) stably integrated into the GeneBLAzer™ NFAT-bla CHO-K1 cell line.

Brand:  Thermo Scientific™ K1637

Product Code. 10676214

  • 996.00 € / Each
Estimated Shipment: 18-12-2024
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Description

Description

The GeneBLAzer™ GRPR-NFAT-bla CHO-K1 cells contain the human Gastrin Releasing Peptide Receptor (GRPR) stably integrated into the GeneBLAzer™ NFAT-bla CHO-K1 cell line. GeneBLAzer™ NFAT-bla CHO-K1 (Cat. No. K1447) contains a beta-lactamase (bla) reporter gene under control of a NFAT response element stably integrated into CHO-K1 cells.

The GRPR-NFAT-bla CHO-K1 cells are functionally validated for Z'-factor and EC50 concentrations using established ligands. In addition, GRPR-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary. Division Arrested cells are irreversibly division arrested using a low-dose treatment of Mitomycin C, and have no apparent toxicity or change in cellular signal transduction.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

NM_005314.2
Division-Arrested Cells
Fluorescence
GRPR
GeneBLAzer™, T-REx™
BLA (Beta-Lactamase)
Division-Arrested Cells Assay Kit
GeneBLAzer™
Cell-based beta lactamase reporter gene
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).

Includes:
• GeneBLAzer™ GRPR CHO-K1 DA cells
• LiveBLAzer™-FRET B/G Loading Kit, 70 μg
• Solution D
• GeneBLAzer™ GRPR CHO-K1 DA Assay Protocol
• LiveBLAzer™-FRET B/G Loading Protocol
• Certificate of Analysis

The GeneBLAzer™ GRPR CHO-K1 DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
GPCRs
Single Cell Clone Origin
8 x 106 Cells
GRPR
CHO-K1
GPCR
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For Research Use Only. Not for use in diagnostic procedures.