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Thermo Scientific Chemicals Guanidine hydrochloride, Molecular Biology Grade

Product Code. 15430467
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100 g
500 g
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500g
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Product Code. 15430467

Brand: Thermo Scientific Chemicals J65661.22

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A protein denaturant | CAS: 50-01-1 | CH6ClN3 | 95.53 g/mol

Guanidine hydrochloride is used for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine hydrochloride is used in RNA isolation to dissociate nucleoproteins and inhibit RNase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Guanidine hydrochloride is used for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine hydrochloride is used in RNA isolation to dissociate nucleoproteins and inhibit RNase.

Solubility
Freely soluble in water

Notes
Protect from heat. Store away from oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 50-01-1
Molecular Formula CH6ClN3
Molecular Weight (g/mol) 95.53
MDL Number MFCD00013026
InChI Key PJJJBBJSCAKJQF-UHFFFAOYSA-N
Synonym guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
PubChem CID 5742
ChEBI CHEBI:32735
IUPAC Name guanidine;hydrochloride
SMILES C(=N)(N)N.Cl

Specifica

Melting Point 178°C to 185°C
Color White
Density 1.34
Quantity 100 g
Beilstein 3591990
Sensitivity Hygroscopic
Merck Index 144562
Solubility Information Freely soluble in water
Formula Weight 95.53
Grade Molecular Biology
Physical Form Crystalline Solid
Chemical Name or Material Guanidine hydrochloride
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compliance-icons
Identificativo prodotto
  • Guanidine hydrochloride, Molecular Biology Grade
Avvertenza
  • Warning
Categoria di pericolo
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
Indicazioni di pericolo
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H332-Harmful if inhaled.
Consigli di prudenza
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
Informazioni supplementari
  • MIXTURE LIST-Contains : Guanidine hydrochloride

RUO – Research Use Only

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