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Thermo Scientific Chemicals Guanidine thiocyanate, Molecular Biology Grade

Product Code. 15496719
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Quantity:
50 g
250 g
500 g
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This item is not returnable. View return policy

A protein denaturant

Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Guanidine thiocyanate is used for RNA isolation and can solubilize proteins. When the compound is used to solubilize proteins it can be removed by dialysis against urea without difficulty. The hybridization of guanidine thiocyanate-solubilize hepatocytes can be used as a method to quantify mRNA from hepatocytes. Blood sample lysate stored in guanidine thiocyanate has been shown to maintain nucleic acid integrity. Research describes guanidine thiocyanate to be ineffective for RNA isolation of plant tissue with a high levels of secondary metabolites and storage proteins.

Solubility
Soluble in water (1420 g/L) at 20°C, and ethanol (5%).

Notes
Light Sensitive. Keep container tightly closed. Store away from oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 593-84-0
Molecular Formula CH5N3·CHNS
MDL Number MFCD00013027
Synonym Guanidine rhodanide

Specifications

Melting Point 118°C to 122°C
Color White
Density 1.29
Quantity 250 g
Beilstein 3563461
Sensitivity Light sensitive
Solubility Information Soluble in water (1420g/L) at 20°C,and ethanol (5%).
Formula Weight 118.16
Grade Molecular Biology
Physical Form Powder
Chemical Name or Material Guanidine thiocyanate
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RUO – Research Use Only

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