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Invitrogen™ Human SIK2 Synthetic Peptide
Synthetic Peptide
Brand: Invitrogen™ PEP1254
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Description
SIK2 Synthetic Peptide, PEP-1254, from Invitrogen.
SNF1LK2 (QIK) is a serine/threonine kinase and is a salt-inducible kinase that belongs to the AMP-activated protein kinase family. SNF1LK2 negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1'alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.
Specifications
| 23235 | |
| purified | |
| Human SIK2 | |
| -20°C | |
| Liquid | |
| Blocking Assay, Control | |
| No | |
| Peptide | |
| RUO - research use only |
| Human | |
| Q9H0K1 | |
| 200 μg/mL | |
| Synthetic Peptide | |
| PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 | |
| SIK2 | |
| 0.02% sodium azide | |
| 50 μg | |
| PBS |
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Product Title
Invitrogen™ Human SIK2 Synthetic Peptide > 50 μg; Unlabeled
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