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IGF1R beta chain Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 € - 410.00 €

Specifications

Antigen IGF1R beta chain
Concentration 0.22 mg/mL
Applications Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16899774
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Proteintech
20254-1-AP-20UL
20 μL
145.00 €
20µL
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16889774
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Proteintech
20254-1-AP-150UL
150 μL
410.00 €
150µL
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Description

Description

This antibody raised against a synthesized polypeptide (CGVLVLRASFDERQPYAH) corresponding to 1332-1348aa of human IGF1R protein recognizes beta subunit of IGF1R.

IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of maligt cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.
Specifications

Specifications

IGF1R beta chain
Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
Mouse, Human, Rat
P08069, P24062, Q60751
16001, 25718, 3480
Peptide
Primary
-20°C
IGF1R
0.22 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
CD221, IGF I receptor, IGF1R, IGFIR, IGFR, JTK13
IGF1R
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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