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iMDK, Tocris Bioscience™

Product Code. 30002021
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Quantity:
10 mg
50 mg
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Description

Suppressor of MDK expression; inhibits PI 3-K signaling

Suppressor of endogenous midkine (MDK) expression. Inhibits PI 3-K signaling in H441 lung adenocarcinoma cells. Selectively attenuates growth of MDK-expressing cancer cells. Induces apoptosis in H441 cells and suppresses growth of H441 cell xenografts in mice.

Chemical Identifiers

CAS 881970-80-5
Molecular Formula C21H13FN2O2S
Molecular Weight (g/mol) 376.405
InChI Key IWFKQTWYILKFGE-UHFFFAOYSA-N
Synonym imdk, 3-2-4-fluorobenzyl imidazo 2,1-b 1,3 thiazol-6-yl-2h-chromen-2-one, 3-2-4-fluorophenyl methyl imidazo 2,1-b thiazol-6-yl-2h-1-benzopyran-2-one, 3-2-4-fluorophenyl methyl imidazo 2,1-b 1,3 thiazol-6-yl chromen-2-one, 3-2-4-fluorophenyl methyl imidazo 2,1-b 1,3-thiazolin-6-yl chromen-2-one
PubChem CID 15991416
IUPAC Name 3-[2-[(4-fluorophenyl)methyl]imidazo[2,1-b][1,3]thiazol-6-yl]chromen-2-one
SMILES C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN4C=C(SC4=N3)CC5=CC=C(C=C5)F

Specifications

Quantity 50 mg
Formula Weight 376.4
Chemical Name or Material iMDK
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