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KB-R7943 mesylate, Tocris Bioscience™

Product Code. 18074232
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Na+/Ca2+ exchange inhibitor (reverse mode)

Potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). Also inhibits the mitochondrial Ca2+ uniporter (MCU; IC50 = 5.5 μM). Does not affect Na+-dependent transport systems or ionotropic glutamate receptors.

Chemical Identifiers

CAS 182004-65-5
Molecular Formula C17H21N3O6S2
Molecular Weight (g/mol) 427.49
InChI Key WGIKEBHIKKWJLG-UHFFFAOYSA-N
Synonym kb-r7943 mesylate, 2-2-4-4-nitrobenzyloxy phenyl ethyl isothiourea mesylate, 4-4-nitrobenzyl oxy phenethyl carbamimidothioate methanesulfonate, s-4-4-nitrobenzyl oxy phenethyl isothiourea methanesulfonate, 2-2-4-4-nitrobenzyloxy phenyl ethyl isothiourea, methane sulfonate, 2-4-4-nitrophenyl methoxy phenyl ethyl sulfanylmethanimidamide; methanesulfonic acid, d0f4fk
PubChem CID 9823846
IUPAC Name methanesulfonic acid;2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl carbamimidothioate
SMILES CS(=O)(=O)O.C1=CC(=CC=C1CCSC(=N)N)OCC2=CC=C(C=C2)[N+](=O)[O-]

Specifications

Quantity 10 mg
Formula Weight 427.49
Percent Purity >99%
Chemical Name or Material KB-R7943 mesylate
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