missing translation for 'onlineSavingsMsg'
Learn More
Learn More
GeneBLAzer™ M5-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M5-NFAT-bla CHO-K1 Cells contain the human Acetylcholine (Muscarinic) Receptor 5 (M5) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Brand: GeneBLAzer™ K1728
Additional Details : Weight : 0.01000kg
Description
- GeneBLAzer™ M5-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 5 (M5) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. no. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
- The GeneBLAzer™ M5-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50concentrations of Carbachol. In addition, GeneBLAzer™ M5-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
- Muscarinic acetylcholine receptor subtype 5 (M5) has an unknown physiological relevance primarily because of low expression levels and the lack of M5 receptor-selective ligands. However, knockout studies have suggested that M5 is involved in modulation of central dopamine function and the tone of cerebral blood vessels.
Specifications
| Store in liquid nitrogen immediately upon receipt | |
| Fluorescent | |
| GeneBLAzer™ M5-NFAT-bla CHO-K1 cells, GeneBLAzer™ M5-NFAT-bla CHO-K1 Assay Protocol, Certificate of Analysis | |
| Dividing Cells |
| Gene Symbol: CHRM5; Accession Number: BC041805.1 | |
| GPCRs | |
| 2 x 106 Cells |