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  7. MDL 100907, Tocris Bioscience™

MDL 100907, Tocris Bioscience™

Product Code. 30002013
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective 5-HT2A antagonist

MDL 100907 is a potent and selective 5-HT2A receptor antagonist (Ki = 0.36 nM, IC50 = 3.3-5.1 nM). MDL 100907 exhibits > 80-fold selectivity for 5-HT2A receptors over other serotonergic receptor subtypes. MDL 100907 is neuroprotective; protects cultured dopaminergic neurons from MPP+ induced toxicity. Antipsychotic agent in vivo.

Chemical Identifiers

CAS 139290-65-6
Molecular Formula C22H28FNO3
Molecular Weight (g/mol) 373.47
MDL Number MFCD00909060
InChI Key HXTGXYRHXAGCFP-UHFFFAOYNA-N
Synonym Volinanserin, unii-ew71ee171j, r-2,3-dimethoxyphenyl 1-4-fluorophenethyl piperidin-4-yl methanol, chembl74355, r-2,3-dimethoxyphenyl-1-2-4-fluorophenyl ethyl piperidin-4-yl methanol, r-+-alpha-2,3-dimethoxyphenyl-1-2-4-fluoro-phenyl ethyl-4-piperidine methanol, volinanserin inn, alpha-2,3-dimethoxyphenyl-1-2-4-fluorophenylethyl-4-piperidine methanol, r-2,3-dimethoxy-phenyl-1-2-4-fluoro-phenyl-ethyl-piperidin-4-yl-methanol
PubChem CID 5311271
IUPAC Name (2,3-dimethoxyphenyl)({1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl})methanol
SMILES COC1=CC=CC(C(O)C2CCN(CCC3=CC=C(F)C=C3)CC2)=C1OC

Specifications

Quantity 50 mg
Formula Weight 373.46
Chemical Name or Material MDL 100907
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