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MFN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13798-1-AP-150UL
This item is not returnable.
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Description
Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.Specifications
MFN1 | |
Polyclonal | |
Unconjugated | |
MFN1 | |
Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
192647, 55669, 67414 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.3 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q811U4, Q8IWA4, Q8R4Z9 | |
MFN1 | |
MFN1 Fusion Protein Ag4762 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |