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MFN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13798-1-AP-20UL
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Description
Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.Specifications
| MFN1 | |
| Polyclonal | |
| Unconjugated | |
| MFN1 | |
| Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 192647, 55669, 67414 | |
| -20°C | |
| Liquid |
| Western Blot, Immunohistochemistry (Paraffin) | |
| 0.3 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q811U4, Q8IWA4, Q8R4Z9 | |
| MFN1 | |
| MFN1 Fusion Protein Ag4762 | |
| 20 μL | |
| Primary | |
| Mouse, Rat, Human | |
| Antibody | |
| IgG |
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