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Invitrogen™ Mouse RIP3 Synthetic Peptide
Synthetic Peptide
Brand: Invitrogen™ PEP0081
This item is not returnable.
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Description
RIP3 Synthetic Peptide, PEP-0081, from Invitrogen.
RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members. RIPK3 is predominantly localized to the cytoplasm, and specifically, are colocalized in the mitochondrion which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor and caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR and that this complex is required for the protective function.
Specifications
| 56532 | |
| purified | |
| Mouse RIP3 | |
| -20°C | |
| Liquid | |
| Blocking Assay, Control | |
| No | |
| Peptide | |
| RUO - research use only |
| Mouse | |
| Q9QZL0 | |
| 200 μg/mL | |
| Synthetic Peptide | |
| PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 | |
| Ripk3 | |
| 0.02% sodium azide | |
| 50 μg | |
| PBS |
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Product Title
Invitrogen™ Mouse RIP3 Synthetic Peptide > 50 μg; Unlabeled
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