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  7. N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98%, Thermo Scientific Chemicals

N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98%, Thermo Scientific Chemicals

Product Code. 11484514
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Quantity:
1 g
5 g
25 g
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Description

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides.

Solubility
Soluble in dimethyl sulfoxide and dimethyl formamide.

Notes
Store in a cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 82911-69-1
Molecular Formula C19H15NO5
Molecular Weight (g/mol) 337.331
MDL Number MFCD00010733
InChI Key WMSUFWLPZLCIHP-UHFFFAOYSA-N
Synonym fmoc-osu, n-9-fluorenylmethoxycarbonyloxy succinimide, fmoc-onsu, 9-fluorenylmethyl succinimidyl carbonate, fmoc n-hydroxysuccinimide ester, 9h-fluoren-9-yl methyl 2,5-dioxopyrrolidin-1-yl carbonate, 9-fluorenylmethyl n-succinimidyl carbonate, 9-fluorenylmethylsuccinimidyl carbonate, 9-fluorenylmethoxycarbonyl-n-hydroxysuccinimide
PubChem CID 134122
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate
SMILES C1CC(=O)N(C1=O)OC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Specifications

Melting Point 150°C to 153°C
Quantity 1 g
UN Number UN3077
Beilstein 3569540
Sensitivity Moisture sensitive
Solubility Information Soluble in dimethyl sulfoxide and dimethyl formamide.
Formula Weight 337.34
Percent Purity 98%
Chemical Name or Material N-(9-Fluorenylmethoxycarbonyloxy)succinimide

Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • N-(9-Fluorenylmethoxycarbonyloxy)succinimide
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • LONG-TERM AQUATIC HAZARD Chronic 2
  • Skin sensitiser Category 1
 Hazard Statement
  • H302-Harmful if swallowed.
  • H317-May cause an allergic skin reaction.
  • H411-Toxic to aquatic life with long lasting effects.
 Precautionary Statement
  • P273-Avoid release to the environment.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
 Supplemental information
  • MIXTURE LIST-Contains : N-(9-Fluorenylmethoxycarbonyloxy)succinimide

RUO – Research Use Only

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