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Tocris Bioscience™ NAV 2729
Selective ARF6 inhibitor
270.00 € - 1080.00 €
Specifications
| Color | Yellow |
|---|---|
| Product Type | Inhibitor |
| CAS | 419547-11-8 |
| Molecular Formula | C25H17ClN4O3 |
| Formula Weight | 456.88g/mol |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18730128
|
Tocris Bioscience™
5986/10 |
10 mg |
270.00 €
10mg |
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|
18755999
|
Tocris Bioscience™
5986/50 |
50 mg |
1080.00 €
50mg |
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Description
Selective ARF6 inhibitor (IC50 = 1.0 μM). Selective for ARF6 over other ARF family members and small GTPases. Inhibits ARF6 activation in uveal melanoma cells in vitro and blocks downstream signaling pathways of oncogenic GNAQ. Reduces tumorigenesis in mouse model of uveal melanoma.Specifications
| Yellow | |
| 419547-11-8 | |
| 456.88g/mol | |
| Store at 4°C |
| Inhibitor | |
| C25H17ClN4O3 | |
| Soluble to 100mM in DMSO | |
| Blocks downstream signaling pathways |
For Research Use Only