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NFE2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11089-1-AP-150UL

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Product Code. 16857933

  • 410.00 € / 150µL

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Description

Description

This is a rabbit polyclonal antibody raised against full-length NFE2 of human origin.

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Specifications

Specifications

NFE2
Polyclonal
Unconjugated
NFE2
Leucine zipper protein NF E2, NF E2, NFE2, p45, p45 NF E2
Rabbit
Antigen Affinity Chromatography
RUO
4778
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q16621
NFE2
NFE2 Fusion Protein Ag1570
150 μL
Primary
Human
Antibody
IgG
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