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NS 1738, Tocris Bioscience™

Product Code. 18015572
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Positive allosteric modulator of α7 nAChR; active in vivo

Selective positive allosteric modulator of α7 nicotinic acetylcholine receptors. Exhibits no substantial activity for α4β2, α3β3 and α1-containing receptors. Displays cognitive-enhancing properties in vivo.

Chemical Identifiers

CAS 501684-93-1
Molecular Formula C14H9Cl2F3N2O2
Molecular Weight (g/mol) 365.133
InChI Key OUDXRNQPVSMGDW-UHFFFAOYSA-N
Synonym n-5-chloro-2-hydroxyphenyl-n'-2-chloro-5-trifluoromethyl phenyl urea, 1-5-chloro-2-hydroxyphenyl-3-2-chloro-5-trifluoromethyl phenyl urea, d0d4lf, urea, n-5-chloro-2-hydroxyphenyl-n'-2-chloro-5-trifluoromethyl phenyl, 1-5-chloro-2-hydroxy-phenyl-3-2-chloro-5-trifluoromethyl-phenyl-urea, 3-5-chloro-2-hydroxyphenyl-1-2-chloro-5-trifluoromethyl phenyl urea, n-3-chloro-6-hydroxy-phenyl-n'-2-chloro-5-trifluoromethyl-phenyl urea
PubChem CID 310378
IUPAC Name 1-(5-chloro-2-hydroxyphenyl)-3-[2-chloro-5-(trifluoromethyl)phenyl]urea
SMILES C1=CC(=C(C=C1C(F)(F)F)NC(=O)NC2=C(C=CC(=C2)Cl)O)Cl

Specifications

Quantity 10 mg
Formula Weight 365.13
Percent Purity 98%
Chemical Name or Material NS 1738
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