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  6. Org 24598, >98%, Tocris Bioscience™

Org 24598, >98%, Tocris Bioscience™

Product Code. 30001362
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Quantity:
10 mg
50 mg
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Description

Inhibitor of GlyT1; derivative of Org 24598 (Cat. No. 4035).

Potent and selective inhibitor of the glial glycine transporter GlyT1b (IC50 = 6.9 nM). Displays negligible activity at GlyT-2, adrenoreceptors, dopamine, 5HT receptors and noradrenaline, dopamine, 5HT and GABA transporters (pIC50 < 4). Active in vivo.

Chemical Identifiers

CAS 372198-97-5
Molecular Formula C19H20F3NO3
Molecular Weight (g/mol) 367.368
InChI Key KZWQAWBTWNPFPW-QGZVFWFLSA-N
Synonym 2-methyl-3r-3-phenyl-3-4-trifluoromethyl phenoxy propyl amino acetic acid, d00lnk, n-methyl-n-3r-3-phenyl-3-4-trifluoromethyl phenoxy propyl-glycine, methyl-r-3-phenyl-3-4-trifluoromethyl-phenoxy-propyl-amino-acetic acid
PubChem CID 5311285
IUPAC Name 2-[methyl-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amino]acetic acid
SMILES CN(CCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F)CC(=O)O

Specifications

Linear Formula C19H20F3NO3
Quantity 50 mg
Solubility Information Soluble to 10mM in water with gentle warming and to 100mM in DMSO
Formula Weight 367.36
Chemical Name or Material N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-glycine
Grade >98%
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