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P 22077, Tocris Bioscience™

Code produit. 18085222
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Quantity:
10 mg
50 mg
Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.
Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.

Description

USP7 inhibitor

Inhibitor of ubiquitin-specific protease (USP) 7 (EC50 = 8.6 μM); also inhibits the closely related deubiquitinase (DUB) USP47. Demonstrates downstream inhibition of HDM2 and claspin in vitro. Inhibits USP7-mediated p53 deubiquitination. Blocks deubiquitination of Tip60 (KAT5) histone lysine acetyltransferase.

Identifiants chimiques

CAS 1247819-59-5
Molecular Formula C12H7F2NO3S2
Molecular Weight (g/mol) 315.31
MDL Number MFCD22580421
InChI Key RMAMGGNACJHXHO-UHFFFAOYSA-N
Synonym 1-5-2,4-difluorophenyl thio-4-nitro-2-thienyl-ethanone, 1-5-2,4-difluoro-phenylsulfanyl-4-nitro-thiophen-2-yl-ethanone, 1-5-2,4-difluorophenylthio-4-nitrothiophen-2-yl ethanone, 1-5-2,4-difluorophenyl thio-4-nitrothiophen-2-yl ethan-1-one, 1-5-2,4-difluorophenyl sulfanyl-4-nitrothiophen-2-yl ethan-1-one, 1-5-2,4-difluorophenyl sulfanyl-4-nitrothiophen-2-yl ethanone, 1-5-2,4-difluorophenyl thio-4-nitro-2-thienyl ethanon
PubChem CID 46931953
IUPAC Name 1-{5-[(2,4-difluorophenyl)sulfanyl]-4-nitrothiophen-2-yl}ethan-1-one
SMILES CC(=O)C1=CC(=C(SC2=C(F)C=C(F)C=C2)S1)[N+]([O-])=O

Spécification

Quantity 50 mg
Formula Weight 315.32
Percent Purity >99%
Chemical Name or Material P 22077
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