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PEG (methoxy group) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA5119587
This item is not returnable.
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Description
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PEG recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
Specifications
| PEG (methoxy group) | |
| Polyclonal | |
| Unconjugated | |
| Poly Ethylene Glycol; Polyethylene Glycol | |
| The immunogen used to generate this antibody corresponds to PEG (methoxy group). | |
| 100 μL | |
| Primary | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid | |
| Chemical |
| Western Blot | |
| 1.36 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Rabbit | |
| Protein A | |
| RUO | |
| Chemical | |
| Antibody | |
| IgG |
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