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PHGDH Mouse anti-Human, CoraLite 488, Clone: 1E8B8, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech CL488-67591-100UL
This item is not returnable.
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Description
PHGDH(D-3-phosphoglycerate dehydrogenase) is also named as 3-PGDH, PGDH3 and belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. It catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor. 3-PGDH deficiency is a rare recessive inborn error in the biosynthesis of the amino acid L-serine characterized clinically by congenital microcephaly, psychomotor retardation, and intractable seizures(PMID:19235232 ).
Specifications
PHGDH | |
Monoclonal | |
1000 μg/mL | |
Mouse | |
Primary | |
Human, Mouse, Rat, Pig | |
IgG1 |
Immunofluorescence | |
1E8B8 | |
CoraLite 488 | |
100 μL | |
26227 | |
Liquid |