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PHGDH Mouse anti-Human, CoraLite 488, Clone: 1E8B8, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech CL488-67591-100UL

Product Code. 17204756

  • 450.00 € / 100µL

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Description

Description

PHGDH(D-3-phosphoglycerate dehydrogenase) is also named as 3-PGDH, PGDH3 and belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. It catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor. 3-PGDH deficiency is a rare recessive inborn error in the biosynthesis of the amino acid L-serine characterized clinically by congenital microcephaly, psychomotor retardation, and intractable seizures(PMID:19235232 ).

Specifications

Specifications

PHGDH
Monoclonal
1000 μg/mL
Mouse
Primary
Human, Mouse, Rat, Pig
IgG1
Immunofluorescence
1E8B8
CoraLite 488
100 μL
26227
Liquid
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