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Gibco™ rhLaminin-521

rhLaminin-521

86.25 € - 680.00 €

Specifications

Cell Type	Stem Cells
Classification	Xeno-free
Culture Type	Stem Cell (Human, iPS - Induced Pluripotent Stem, Embryonic)
Product Type	Extracellular Matrix
pH	6 to 8

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Products 2

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
15481044 View Documents missing translation for 'viewProductCertificates'	Gibco™ A29249	1 mg	680.00 € 100µg		Please sign in to purchase this item. Need a web account? Register with us today!



15461945 View Documents missing translation for 'viewProductCertificates'	Gibco™ A29248	100μg	86.25 € 100µg		Please sign in to purchase this item. Need a web account? Register with us today!

Description

Recombinant human Laminin 521 (rhLaminin-521) is a recombinant human protein that provides a defined surface for feeder-free culture of human pluripotent stem cells (PSCs). When used with Essential 8™ Medium, rhLaminin-521 has been proven to promote cellular survival under stressful conditions in the absence of small molecule inhibitors. rhLaminin-521 has been shown to support PSC growth for >20 passages without any signs of karyotypic abnormalities and to maintain the ability of PSCs to differentiate into all three germ line lineages. rhLaminin-521 also provides optimum reprogramming efficiency of human somatic cells as well as human pluripotent stem cell survival during feeder-dependent to feeder-free transitions when used in conjunction with Essential 8 Medium. For a kit that combines the medium and substrate, see the Essential 8™ Adaptation Kit.

rhLaminin-521 is:

Robust—transition cells between feeder-dependent and feeder-free culture systems with minimal effort

Efficient—easily reprogram human fibroblasts to pluripotent stem cells

Physiologically relevant—expand cells with minimal differentiation

Scalable—passage stem cell lines as single cells with no impact to genetic stability

Trouble-free transition
When used with Essential 8 Medium, rhLaminin-521 provides a robust culture matrix that supports pluripotent stem cell adherence and expansion during the transition from feeder-dependent culture systems.

Efficient reprogramming
rhLaminin-521 has been shown to increase the number of colonies obtained during reprogramming of human fibroblasts, which can be important for in vitro disease modeling.

Confident expansion
rhLaminin-521 is expressed in blastocysts and therefore provides an environment mimicking the human stem cell niche.

Easy scale-up
rhLaminin-521 promotes stable pluripotent stem cell maintenance as single cells in the absence of ROCK inhibitors.

Specifications

Cell Type	Stem Cells
Culture Type	Stem Cell (Human, iPS - Induced Pluripotent Stem, Embryonic)
pH	6 to 8
Shipping Condition	Dry Ice

Classification	Xeno-free
Product Type	Extracellular Matrix
Purity or Quality Grade	hESC-Qualified
Source	Xeno-Free

For Research Use Only. Not for use in diagnostic procedures.

Gibco™ rhLaminin-521

Specifications

Description

Specifications

Documents