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  6. Sodium glycocholate hydrate, 98%, Thermo Scientific Chemicals

Sodium glycocholate hydrate, 98%, Thermo Scientific Chemicals

Product Code. 10772833
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Quantity:
5 g
25 g
Packaging:
Glass bottle

Description

Sodium glycocholate hydrate, CAS # 207614-05-9, is a bile acid glycine conjugate and also an ionic biologic detergent.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Sodium glycocholate hydrate is a conjugated bile salt
  • It is an ionic detergent

Applications

  • Sodium glycocholate hydrate is used to determine serum total bile acids by fluorimetric and enzymatic methods.
  • It has also been used in in vitro studies to investigate its effect on micelle formation and solubilization of testosterone.
  • This compound is considered a detergent used to solubilize fats for absorption.
  • This chemical product is synthetically derived from a natural compound, cholic acid.
  • Sodium glycocholate hydrate has been tested in the laboratory for its ability to form a liposomal delivery system to enhance oral insulin delivery. The in vitro results demonstrated that sodium glycocholate liposomes showed promising activity and can be useful to create a new approach to orally deliver insulin more efficiently.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 207614-05-9
Molecular Formula C26H42NNaO6
Molecular Weight (g/mol) 487.61
MDL Number MFCD09037360
InChI Key OABYVIYXWMZFFJ-XIMBWSGONA-M
Synonym glycocholic acid sodium salt hydrate, sodium glycocholate hydrate, c26h42no6.na.2h2o, sodium glycocholate dihydrate
PubChem CID 45051920
IUPAC Name sodium;2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetate;dihydrate
SMILES [Na+].[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCC([O-])=O

Specifications

Color Colorless to Yellow
Infrared Spectrum Authentic
Assay Percent Range 0.98
Packaging Glass bottle
Quantity 5 g
Specific Rotation Condition + 29.50 (20.00°C c=1,H2O)
Specific Rotation +28° to +31° (20°C, 589nm) (c=1, H2O) on dry basis
Formula Weight 487.61
Percent Purity ≥97.5% (on dry basis) (Total base)
Physical Form Liquid
Chemical Name or Material Sodium glycocholate hydrate, 0.98
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Safety and Handling

compliance-icons
Product Identifier
  • Sodium glycocholate hydrate
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H315-Causes skin irritation.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.

RUO – Research Use Only

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