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SPDP, MedChemExpress
MedChemExpress SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
Brand: Medchem Express HY-100216
Description
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).Specifications
SPDP | |
White | |
C12H12N2O4S2 | |
SPDP Crosslinker | |
O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2 | |
312.36 | |
Research |
68181-17-9 | |
Research | |
10 mg | |
DMSO : 155 mg/mL (496.22 mM; Need ultrasonic) | |
312.36 | |
97.0% | |
Solid |
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Research purposes only