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  6. TC 2559 difumarate, Tocris Bioscience™

TC 2559 difumarate, Tocris Bioscience™

Product Code. 30001431
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Quantity:
10 mg
50 mg
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Description

Selective partial agonist at α4β2 receptors

Subtype-selective partial agonist for α4β2 nicotinic acetylcholine receptors (EC50 values are 0.18, 12.5, 14.0, > 30, > 100 and > 100 μM for α4β2, α4β4, α2β4, α3β4, α3β2 and α7 receptor subtypes respectively). Displays selectivity for (α4)2(β2)3 receptor stoichiometry and enhanced CNS-PNS selectivity ratio. Attenuates scopolamine-induced cognitive deficits in a step-through passive avoidance task.

Chemical Identifiers

CAS 212332-35-9
Molecular Formula C20H26N2O9
Molecular Weight (g/mol) 438.433
InChI Key GEWVPSJQGJBDLM-SLNOCBGISA-N
Synonym tc 2559 difumarate
PubChem CID 122715498
IUPAC Name but-2-enedioic acid;(E)-4-(5-ethoxypyridin-3-yl)-N-methylbut-3-en-1-amine
SMILES CCOC1=CN=CC(=C1)C=CCCNC.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O

Specifications

Quantity 10 mg
Formula Weight 438.43
Percent Purity >98%
Chemical Name or Material TC 2559 difumarate
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