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Tetrahydro-4H-pyran-4-one, 98%, Thermo Scientific Chemicals

Product Code. 11449316
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Quantity:
1 g
5 g
25 g
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It is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes. The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. It is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. It is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes. The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. It is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. It is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3

Solubility
Very soluble in water.

Notes
Store away from strong bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 29943-42-8
Molecular Formula C5H8O2
Molecular Weight (g/mol) 100.117
MDL Number MFCD00006581
InChI Key JMJRYTGVHCAYCT-UHFFFAOYSA-N
Synonym tetrahydro-4h-pyran-4-one, 4-oxotetrahydropyran, tetrahydropyran-4-one, dihydro-2h-pyran-4 3h-one, 4h-pyran-4-one, tetrahydro, 4-thp, tetrahydro-2h-pyran-4-one, tetrahydro-pyran-4-one, 4-oxotetrahydopyran, tetrahydro-.gamma.-pyrone
PubChem CID 121599
IUPAC Name oxan-4-one
SMILES C1COCCC1=O

Specifications

Density 1.084
Boiling Point 165°C to 167°C
Flash Point 62°C (144°F)
Refractive Index 1.453
Quantity 1 g
Beilstein 106463
Solubility Information Very soluble in water.
Formula Weight 100.12
Percent Purity 98%
Chemical Name or Material Tetrahydro-4H-pyran-4-one
compliance-icons
Product Identifier
  • Tetrahydro-4H-pyran-4-one
Signal Word
  • Warning
Hazard Category
  • Flammable liquid Category 3
Hazard Statement
  • H226-Flammable liquid and vapour.
Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
Supplemental information
  • MIXTURE LIST-Contains : Tetrahydro-4H-pyran-4-one

RUO – Research Use Only

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