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TMEM41B Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 29270-1-AP-20UL
This item is not returnable.
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Description
Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.
Specifications
| TMEM41B | |
| Polyclonal | |
| Unconjugated | |
| 20 μL | |
| 440026 | |
| Liquid |
| Western Blot, Immunohistochemistry, Immunofluorescence, ELISA | |
| 400 μg/mL | |
| Rabbit | |
| Primary | |
| Human, Mouse |