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  8. Tranilast, Tocris Bioscience™

Tranilast, Tocris Bioscience™

Product Code. 18782654
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Quantity:
50 mg
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This item is not returnable. View return policy

Description

Antiallergic; inhibits inflammatory mediator release from mast cells

Tranilast is an antiallergic via inhibition of chemical mediator release from mast cells. Shown to be an effective inhibitor of angiogenesis. Demonstrated to antagonize the effects of angiotensin II on human arteries, possibly by an interaction at the level of the AT1 receptor. Inhibits TRPV2-mediated responses; binds to Aβ40 monomers and increases Aβ40 fibrillation.

Chemical Identifiers

CAS 53902-12-8
Molecular Formula C18H17NO5
Molecular Weight (g/mol) 327.34
MDL Number MFCD00864787
InChI Key NZHGWWWHIYHZNX-CSKARUKUSA-N
Synonym tranilast, rizaben, trans-tranilast, tranilastum, n-3,4-dimethoxycinnamoyl anthranilic acid, tranilastum inn-latin, tranilast usan:inn:jan, tranpro, unii-hvf50smy6e, rizaben tn
PubChem CID 5282230
ChEBI CHEBI:77572
IUPAC Name 2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benzoic acid
SMILES COC1=CC=C(\C=C\C(=O)NC2=CC=CC=C2C(O)=O)C=C1OC

Specifications

Quantity 50 mg
Formula Weight 327.34
Percent Purity >99%
Chemical Name or Material Tranilast
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