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Trifluoroacetic acid, 99.5+%, Thermo Scientific Chemicals
Description
The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and ceramic compounds. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. It finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Specifications
Specifications
| Melting Point | °C to 15°C |
| Boiling Point | 72°C to 73°C |
| Assay Percent Range | >99.5% |
| Linear Formula | CF3CO2H |
| UN Number | UN2699 |
| Beilstein | 742035 |
| Merck Index | 14,9681 |
| Solubility Information | Miscible with water,ether,acetone,ethanol,benzene,hexane and carbon tetrachloride. |
| Formula Weight | 114.02 |
| Percent Purity | ≥99.5% |
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Safety and Handling
- Trifluoroacetic acid
- Danger
- Acute toxicity Category 4
- LONG-TERM AQUATIC HAZARD Chronic 3
- Serious eye damage/eye irritation Category 1
- Skin corrosion/irritation Category 1 A
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H332-Harmful if inhaled.
- H412-Harmful to aquatic life with long lasting effects.
- EUH071-Corrosive to the respiratory tract.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : Trifluoroacetic acid
RUO – Research Use Only