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MedChemExpress Trifluridine/tipiracil hydrochloride mixture
MedChemExpress Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent.
Brand: MedChemExpress HY-16478
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Description
The composition of Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). Trifluridine/tipiracil hydrochloride mixture (TAS-102) shows the antitumor activity mainly via the inhibition of thymidylate synthase (TS) and incorporation into DNA.
Specifications
435.76 g/mol | |
4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) | |
98.0% | |
H2O : 100 mg/mL (229.48 mM∣Need ultrasonic) ∣DMF : 20 mg/mL (45.90 mM∣Need ultrasonic) ∣DMSO : 2.34 mg/mL (5.37 mM∣Need ultrasonic and warming) | |
733030-01-8 |
Reference compound | |
Room temperature | |
5 mg | |
Cancer-programmed cell death | |
TAS-102 |
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