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Tocris Bioscience™ TRPC6-PAM-C20
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Product Code. p-7182959
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18725706

Brand: Tocris Bioscience™ 6875/10

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Selective TRPC6 positive allosteric modulator

TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. Selectively activates TRPC6 over other TRP channels. Also activates TRPA1. Induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 (EC50 = 2.37 μM). Potentiates OAG (1-oleoyl-1-acetyl-sn-glycerol)-induced Ca2+ influx in human platelets, and enhances OAG-induced platelet aggregation.
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Specifications

Chemical Name or Material 3-(3-,4-Dihydro-6,7-dimethoxy-3,3-dimethyl-1-isoquinolinyl)-2H-1-benzopyran-2-one
CAS 667427-75-0
Quantity 10 mg
Molecular Formula C22H21NO4
Purity 98%
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