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Tocris Bioscience™ AZD 8055

Highly potent and selective mTOR inhibitor

Brand:  Tocris Bioscience™ 7840/50

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Product Code. 30000027

  • 521.00 € / 50mg

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Description

Description

AZD 8055 is a highly potent, selective and ATP-competitive mTOR inhibitor (IC50 = 0.8 nM). Inhibits growth and induces autophagy in a range of cancer cell lines and xenografts, including NSCLC and glioblastoma (IC50 values are 20, 50 and 53 nM in H838, A549 and U87MG cell lines, respectively). Orally bioavailable.
Specifications

Specifications

5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
50 mg
C25H31N5O4
1009298-09-2
mTOR Inhibitors
0.98
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