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Tocris Bioscience™ BAG 956
Dual PI 3-kinase and PDPK1 (PDK1) inhibitor
240.00 € - 909.00 €
Specifications
Purity | 98% |
---|---|
Content And Storage | Store at -20°C |
Product Type | BAG 956 |
Molecular Weight (g/mol) | 427.5 |
Inhibitors | BAG 956 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18025612
|
Tocris Bioscience™
3606/10 |
10 mg |
240.00 €
10mg |
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18024652
|
Tocris Bioscience™
3606/50 |
50 mg |
909.00 €
50mg |
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Description
Dual PDPK1 (PDK1) and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDPK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively). Inhibits cellular AKT phosphorylation at Thr308. Blocks cell proliferation, causing arrest in G1 phase of the cell cycle. Slows tumor progression in mouse xenograft models.Specifications
98% | |
BAG 956 | |
BAG 956 |
Store at -20°C | |
427.5 |
For Research Use Only
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