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Estrogen Receptor Ab-11 Mouse Monoclonal Antibody, Epredia™
Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor Ab-11, Mouse Monoclonal Antibody.
Brand: Epredia MS-354-P1
This item is not returnable.
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Description
The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.Host Species: Mouse
Clone: 1D5
Isotype: IgG1/κ
Species Reactivity: Human, Monkey, Mouse and Rat. Others not known.
Epitope: N-terminal domain
Immunogen: Recombinant human estrogen receptor protein
Molecular Weight: 67 kDa
Positive Control: MCF-7 cells, Breast CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Specifications
| Estrogen Receptor Ab-11 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| Steroids Hormones and Growth Factors | |
| Human, Mouse, Non-human Primate, Rat | |
| IgG2a κ |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1D5 | |
| Unconjugated | |
| Recombinant human estrogen receptor protein | |
| ASR, IVD | |
| Primary | |
| Concentrated |
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