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Invitrogen™ Human Sortilin ELISA Kit
Human Sortilin quantitates human Sortilin in serum, plasma, supernatant.
Brand: Invitrogen™ EH433RB
This item is not returnable.
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Description
Human Sortilin quantitates human Sortilin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Sortilin.
Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.
Specifications
| 100 kDa NT receptor; 2900053A11Rik; AI852375; glycoprotein 110; glycoprotein 95; Gp110; Gp95; LDLCQ6; mNTR3; neurotensin receptor 3; NT3; NTR3; Nts3; Ntsr3; Sort1; Sortilin; sortilin 1 | |
| 0.81 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| Sort1 | |
| <10% | |
| HRP | |
| Research Use Only | |
| 2°C to 8°C | |
| 1 hr 20 min |
| 0.819 to 200 ng/mL | |
| Biotin | |
| Plasma, Serum, Supernatant | |
| Q99523 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 96 Tests | |
| Serum, 50 μL; Supernatant, 50 μL; Plasma, 50 μL | |
| Sortilin | |
| 4 hr 45 min |
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