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Proteintech HumanKine™ recombinant human IL-34 protein
HumanKine™ recombinant protein
Brand: Proteintech HZ-1316-1000UG
This item is not returnable.
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Description
IL-34 is a 6-α-helix, proinflammatory cytokine that serves as a ligand for colony-stimulating factor-1 receptor (CSF1R). It is expressed most abundantly by spleen cells. It primarily stimulates human peripheral blood monocyte proliferation and macrophage colony formation. It is also required for Langerhans cell and microglia development. IL-34 has been shown to play a protective role in cancer and Alzheimer’s disease, but it can promote the progression of several autoimmune, inflammatory, and metabolic diseases. As such IL-34 could be used as a biomarker to mark the progression of these diseases (PMID: 22579672, 27577879, 31940023).Specifications
| Q6ZMJ4 | |
| 146433 | |
| 1000 μg | |
| Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.) | |
| Human | |
| Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA). | |
| >95% |
| 50 mM Acetate pH 4.5 + 75 mM NaCl, See Certificate of Analysis for details | |
| 68 and 38 kDa | |
| HEK293 | |
| <1 EU/μg | |
| Recombinant | |
| Lyophilized |