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  5. Tocris Bioscience™ Pyridostatin pentahydrochloride
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Tocris Bioscience™ Pyridostatin pentahydrochloride

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

Brand:  Tocris Bioscience™ 4763/10

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Product Code. 18744719

  • 308.00 € / 10mg

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Description

Description

Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).
Specifications

Specifications

95%
1781882-65-2
10 mg
M.W. (Observed): 778.94
4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride
Desiccate at RT
Pyridostatin pentahydrochloride
Pyridostatin pentahydrochloride
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