missing translation for 'onlineSavingsMsg'
Learn More

Tetraethyl methylenediphosphonate, 98+%, Thermo Scientific Chemicals

Product Code. 11451898
5 g
Click to view available options
Quantity:
5 g
25 g
100 g
This item is not returnable. View return policy
This item is not returnable. View return policy

Tetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.

Solubility
Slightly miscible with water.

Notes
Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1660-94-2
Molecular Formula C9H22O6P2
Molecular Weight (g/mol) 288.22
MDL Number MFCD00039887
InChI Key STJWVOQLJPNAQL-UHFFFAOYSA-N
Synonym tetraethyl methylenediphosphonate, tetraethyl methanediphosphonate, tetraethyl diphosphonomethane, methylenebis diethylphosphonate, tetraethyl methylenebisphosphonate, phosphonic acid, methylenebis-, tetraethyl ester, methylenebis diethoxyphosphine oxide, methylenebisphosphonic acid, tetraethyl ester, phosphonic acid, methylenedi-, tetraethyl ester, methylenedi phosphonic acid tetraethyl ester
PubChem CID 15455
SMILES CCOP(=O)(CP(=O)(OCC)OCC)OCC

Specifications

Density 1.162
Boiling Point 151°C to 153°C (1.2 mmHg)
Flash Point >110°C (230°F)
Refractive Index 1.44
Quantity 5 g
Beilstein 1813241
Solubility Information Slightly miscible with water.
IUPAC Name diethyl [(diethoxyphosphoryl)methyl]phosphonate
Formula Weight 288.22
Percent Purity ≥98%
Chemical Name or Material Tetraethyl methylenediphosphonate
Show More Show Less

RUO – Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Tetraethyl methylenediphosphonate, 98+%, Thermo Scientific Chemicals >

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.