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Tetraethyl methylenediphosphonate, 98+%, Thermo Scientific Chemicals
Description
Tetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Tetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.
Solubility
Slightly miscible with water.
Notes
Incompatible with strong oxidizing agents.
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Specifications
Specifications
Density | 1.162 |
Boiling Point | 151°C to 153°C (1.2 mmHg) |
Flash Point | >110°C (230°F) |
Refractive Index | 1.44 |
Quantity | 5 g |
Beilstein | 1813241 |
Solubility Information | Slightly miscible with water. |
IUPAC Name | diethyl [(diethoxyphosphoryl)methyl]phosphonate |
Formula Weight | 288.22 |
Percent Purity | ≥98% |
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RUO – Research Use Only
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