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Tocris Bioscience™ WH-4-023

Potent and selective Lck and Src inhibitor; also inhibits SIK

Brand:  Tocris Bioscience™ 5413/50

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Product Code. 18706648

  • 1445.00 € / 50mg

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Description

Description

WH-4-023 is a potent and selective Lck and Src inhibitor (IC50 values are 2 and 6 nM respectively). Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases. Supports self-renewal of naive hESCs in combination with PD 0325901, CHIR 99021 and SB 590885 .
Specifications

Specifications

>98%
50 mg
568.67
KIN112
WH-4-023
WH-4-023
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